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The ABO blood group system is a classification of human blood based on the presence or absence of specific antigens and antibodies on the surface of red blood cells. The four main blood types are A, B, AB, and O, determined by the presence or absence of the A and B antigens.


The A antigen is responsible for the A blood type, while the B antigen is responsible for the B blood type. Individuals with both A and B antigens have an AB blood type, while those without either antigen have an O blood type. The Rh factor, which refers to the presence or absence of the Rh antigen, can also be used to further classify blood types into positive (Rh+) or negative (Rh-) categories.


According to various sources, including Wikipedia, WebMD, and Britannica, there are four main blood groups: A, B, AB, and O. These blood groups are determined by the presence or absence of the A and B antigens, which are inherited from one's parents. The discovery of the ABO blood group system was made in the early 20th century by Austrian immunologist Karl Landsteiner.


In his research, Landsteiner found that certain people had blood that would agglutinate (clump together) when mixed with blood from other individuals. He identified three distinct blood types: A, B, and O. Later, he discovered a fourth type, AB, which has both A and B antigens.


Since then, the ABO blood group system has become a crucial tool in transfusion medicine, allowing medical professionals to match blood donors and recipients to ensure safe and successful transfusions. The system has also been used in forensic science, anthropology, and genetic research.


In conclusion, the ABO blood group system is a fundamental classification of human blood based on the presence or absence of specific antigens and antibodies. With four main blood types - A, B, AB, and O - this system has revolutionized the field of transfusion medicine and has far-reaching implications for medical and scientific research.

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